Komal Nayak completed her BSc (Hons) in Biomedical Sciences in 2007 and an MSc by Research in 2010 at the University of Central Lancashire, UK. In 2011, she worked at Imperial College London, studying the effects of inflammation on neuronal iron metabolism in Parkinson’s Disease.
Since 2012, Komal has been part of Prof Zilbauer’s group, where she has gained extensive experience with human gut organoid culture models. As a Senior Scientist, she leads projects related to gut organoids, including their molecular profiling, the development of a biobank, and functional assays. Over the decade, she has successfully established a large living biobank, housing over 1,000 frozen organoid lines, a vital resource for ongoing research. Her research focuses on understanding the role of epigenetic mechanisms in regulating intestinal epithelial stem-cell function in both health and disease, particularly in the context of Inflammatory Bowel Diseases.
Cells of the human intestinal tract mapped across space and time.
Elmentaite R, Kumasaka N, Roberts K, Fleming A, Dann E, King HW, Kleshchevnikov V, Dabrowska M, Pritchard S, Bolt L, Vieira SF, Mamanova L, Huang N, Perrone F, Goh Kai'En I, Lisgo SN, Katan M, Leonard S, Oliver TRW, Hook CE, Nayak K, Campos LS, Domínguez Conde C, Stephenson E, Engelbert J, Botting RA, Polanski K, van Dongen S, Patel M, Morgan MD, Marioni JC, Bayraktar OA, Meyer KB, He X, Barker RA, Uhlig HH, Mahbubani KT, Saeb-Parsy K, Zilbauer M, Clatworthy MR, Haniffa M, James KR, Teichmann SA
Nature. 2021 Sep;597(7875):250-255. doi: 10.1038/s41586-021-03852-1. Epub 2021 Sep 8.
